Giovanni Cannarozzo, MD,1 Mario Sannino, MD,1 Federica Tamburi, MD,2 Cristiano Morini, MD,1 and Steven Paul Nistico’, MD3 
1Master’s degree course ‘‘Laser in Dermatology,’’ University of Rome, Tor Vergata, Italy.
2Unit of Dermatology, Complesso Integrato Columbus, Catholic University, Rome, Italy.
3Department of Health Sciences, University ‘‘Magna Graecia,’’ Catanzaro, Italy.


Abstract Objective: Flash lamp pulsed dye laser (FPDL) was used in a selected group of patients with hypertrophic scars and keloids. Objective of the study was to assess the efficacy on a large number of cases. Background data: FPDL is a nonablative technology, typically used in vascular malformation therapy because of its specificity for hemoglobin.

Methods: A total of 59 patients (33 males and 26 females, mean age 37.5 years) affected by hypertrophic postsurgical scars and keloids, underwent from four to six treatment sessions with a flash lamp pumped pulsed dye laser. Clinical follow-up was performed 6 months after the last treatment. Results were judged by blind observers.

Results: A total of 29 patients out of 59 (49.1%) achieved excellent clearance, 15 patients (25.4%) achieved good to moderate clearance, and 12 patients (20.4%) obtained slight improvement. Only three subjects (5%) had little or no removal of their lesion. Treatment was well tolerated with minor and transient side effects.

Conclusions: FPDL is known as a safe and effective treatment for different dermatological lesions in which skin microvessels play a key role in pathogenesis or development. This laser was effective when applied to hypertrophic scars and keloids. Further studies in a larger set of patients, however, are required to assess a standardized and reproducible method for treating these lesions.

[pdfjs-viewer url=”http%3A%2F%2Fgild-ftp.com%2Fwp-content%2Fuploads%2F2017%2F09%2Fflash_PHO-2015-3895-Cannarozzo_1P-2.pdf” viewer_width=100% viewer_height=1360px fullscreen=true download=true print=true]