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Maurizio Filippini, MD,1 Ester Del Duca, MD,2 Francesca Negosanti, MD,3,4 Diletta Bonciani, MD,5 Luca Negosanti, MD,6 Mario Sannino, MD,4 Giovanni Cannarozzo, MD,4 and Steven Paul Nistico’, MD4,7

1Department of Obstetric and Gynecology, Hospital State of Republic of San Marino, San Marino, Republic of San Marino.
2Department of Dermatology, University of Rome Tor Vergata, Rome, Italy.
3Dermatology Center srl, Bologna, Italy.
4‘‘Laser in Dermatology,’’ University of Rome Tor Vergata, Rome, Italy.
5Section of Dermatology, Department of Surgery and Translational Medicine, University of Florence, Ospedale ‘‘Piero Palagi,’’ Florence, Italy.
6Division of Plastic Surgery, S.Orsola-Malpighi University Hospital Bologna, Bologna, Italy.
7Dermatology Department of Health Sciences, ‘‘Magna Grecia’’ University of Catanzaro, Catanzaro, Italy.

Abstract

The CO2 laser has become the gold standard treatment in dermatologic surgery for the treatment of a large number of skin and mucosal lesions. The introduction of the fractional micro-ablative technology represented an integration to the ablative resurfacing technique, reducing the healing time and the side effects. Vaginal rejuvenation performed with this technique is a minimally invasive procedure that stimulates internal tissues of the female lower genital tract to regenerate the mucosa, improving tissue trophism and restoring the correct functionality. Our experience in 386 menopausal women, affected with vulvo-vaginal atrophy (VVA) and treated with fractional micro-ablative CO2 laser, demonstrated that it is very useful in the treatment of this condition. Fractional micro-ablative CO2 laser seems to reduce symptoms related to vaginal atrophy. The beneficial effects were reported just after the first session and confirmed 12 months after the previous session. The treatment is quite comfortable and painless.

Keywords: vulvo-vaginal atrophy (VVA), genitourinary syndrome, vulvo-vaginal rejuvenation, fractional micro-ablative laser CO2 technology.

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